Most PCB amps that have been produced have been poorer than tube amps, for reasons having nothing to do with the PCB. Like plastic bobbins in transformers, this does nothing to change the tone. The other poor practices that go with a cost-cutting attitude that were introduced at the same time may, but PCBs are unfairly indicted.
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, Added: 15 Oct 2007
http://www.geofex.com/Article_Folders/pt-to-pt/pt-to-pt.htm